SIS
SIS (semantics implementation system, 1972–1979) used partial evaluation to run programs according to their denotational semantics.
It included an SLR(1) parser generator, a call-by-need lambda-notation interpreter, and a translator from denotational semantics specifications to lambda-expressions.
SIS was written in BCPL at Oxford (1972–1976) and Aarhus (1976–1979), and ported to several operating systems.
My dissertation (1975) describes an early version of SIS. The SIS Reference Manual and Tested Examples document the final version.